Myasthenia Graves Research Group

 

MG Research

Genome Wide Association Study In Myasthenia Gravis (GWAS)

Principal Investigator Dan Drachman, MD, Bryan Traynor, MD, PhD
Site-PI Michael Benatar, MD, PhD
Summary The purpose of this project is to conduct a powerful Genome-wide search for genetic factors that are associated with myasthenia gravis (MG), and that are likely to play a role in the disease process. We will use DNA from 1100 MG patients, obtained by collaboration among 14 institutions. Analysis will be carried out in collaboration with the Laboratory of Neurogenetics at the NIH. An improved understanding of the genetic alterations in MG may lead toward a greater understanding of the cause of disease and help to identify specific genetic targets for therapy.
Eligibility criteria
  • Ocular or generalized myasthenia gravis
  • Antibodies directed against the acetylcholine receptor
  • Caucasian
Funding agency Myasthenia Gravis Foundation of America (MGFA)
Collaborators Dan Drachman, MD
Bryan Traynor, MD, PhD
Project manager
Contact information Email:
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Presentations / Publications