Myasthenia Graves Research Group


MG Research

Thymectomy Trial In Non-Thymomatous Myasthenia Gravis Patients Receiving Prednisone Therapy (MGTX)

Principal Investigator Gary Cutter, PhD, Gil Wolfe, MD
Site-PI Michael Benatar, MD, PhD
Summary The purpose of this multi-center, randomized controlled trial is to determine if extended trans-sternal thymectomy combined with prednisone therapy is more beneficial in treating patients with non-thymomatous myasthenia gravis than prednisone alone.
Eligibility criteria
  • Generalized myasthenia gravis, onset within last 5 years
  • Positive acetylcholine receptor binding antibodies
  • Age 18-65
  • MGFA class II-IV
  • No immunosuppressive therapy other than prednisone for one year
  • No thymoma
Funding agency National Institutes of Health
Collaborators Gil Wolfe, MD
Gary Cutter, PhD
Henry Kaminski, MD
Project manager

Alexandra Waltz, MA
Phone: 305-243-3799

Contact information
Presentations / Publications